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一、多肽藥研發(fā)的技術(shù)瓶頸多肽合成的困難程度從中國牛胰島素的合成。胰島素由A、B兩條肽鏈，共17種51個氨基酸組成。人工合成胰島素，首先要把氨基酸按照一定的順序連結(jié)起來，組成A鏈、B鏈，然后再把A、B兩條鏈連在一起。由于當(dāng)時還沒出現(xiàn)固相合成的...

Thedifficultiesinvolvedinscalingupreactionsfromlaboratorytoprocessscalearewellknown,especiallywhendangerousmaterialsarei...

ThisapplicationnotewilldemonstratetheH-CubePro™’sincreasedproductivityinthehydrogenationofD-glucosetoD-sorbitol,wh...

Thepharmaceuticalindustryiscontinuallysearchingtoautomatetechniquesforrapidoptimizationorlibraryproduction.Theautomation...

ThehydrogenationofaseriesoffunctionalgroupshasbeenperformedusingH-Cube®,anovelcontinuous-flowmicrofluidichydrogenati...

INTRODUCTIONSelectivecatalytichydrogenationofa-b-unsaturatedaldehydesisanimportantstepintheindustrialpreparationoffinech...

TheH-CubePro™improvesupontheoriginalH-Cube®byofferinggreaterhydrogenproduction（upto60mL/min）forhigherthroughpu...

TheX-Cube™isacontinuousflowreactor,capableofperformingchemicalreactionunderinertconditions,temperaturesupto200°Cａn...